Gunmen stormed a home in a township outside the South African city of Pietermaritzburg and killed 10 members of the same family, police have said.
Police did not give a motive for the shooting.
Seven women and three men were killed, the police ministry said in a statement.
South Africa has one of the world's highest murder rates, with about 20,000 murders recorded every year out of a population of 60 million.
"It's a crime scene, terrible. Too many people were lost here," Police Minister Bheki Cele said in comments broadcast on public broadcaster SABC from Pietermaritzburg in KwaZulu-Natal province.
Cele said police management needed to sit down to talk about whether the province needed more police resources.
A Reuters photojournalist at the scene of the shooting saw a mortuary van in the yard of the homestead into which bodies of those killed were being loaded on a stretcher. Worried members of the community looked on.
Israel struck multiple targets linked to the Houthi movement in Yemen on Thursday, including Sanaa International Airport, while the chief of the World Health Organisation (WHO) was boarding a plane.
Syria's new authorities on Thursday launched a security crackdown in a coastal region where 14 policemen were killed a day before, vowing to pursue "remnants" of the ousted Bashar al-Assad government accused of the attack, state media reported.
The United Nations peacekeeping force in Lebanon (UNIFIL) called on Thursday for a timely Israeli withdrawal from south Lebanon, citing what it called Israeli violations of a November 27 ceasefire agreement with Iran-backed Lebanese armed group Hezbollah.
Described as a "reluctant king" in his first stint as prime minister, the soft-spoken Manmohan Singh, who died on Thursday at the age of 92, was arguably one of India's most successful leaders.
The Azerbaijan Airlines flight that crashed in Kazakhstan on Wednesday was downed by a Russian air defence system, four sources in Azerbaijan with knowledge of the investigation told Reuters.
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